Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1977 Jul;7(2):219-24.
doi: 10.1007/BF01969976.

The role of histamine in wound healing I. The effect of high doses of histamine on collagen and glycosoaminoglycan content in wounds

R Dabrowski, C Maśliński, A Olczak

The role of histamine in wound healing I. The effect of high doses of histamine on collagen and glycosoaminoglycan content in wounds

R Dabrowski et al. Agents Actions. 1977 Jul.

Abstract

The effect of high doses of histamine (Hi) on collagen and glycosoaminoglycan (GAG) content in skin wounds of rats was studied on days 1, 3, 5, 10 and 14 after wounding. Injection of high doses of Hi into the wounded area inhibited colagen production, collagen polymerization and GAG synthesis; levels of chondroitin sulphates (chondroitin-4,6-sulphate and dermatan sulphate) and hyaluronic acid were decreased.

PubMed Disclaimer

References

    1. J Pharmacol Exp Ther. 1975 Jun;193(3):910-7 - PubMed
    1. J Cell Biol. 1965 Oct;27(1):83-106 - PubMed
    1. Life Sci. 1970 Feb 15;9(4):189-202 - PubMed
    1. Biochem J. 1971 Nov;125(1):37-46 - PubMed
    1. J Biophys Biochem Cytol. 1961 Dec;11:571-605 - PubMed