[Electroretinographic changes in experimental metalloses]

Abstract

In this experimental study the authors studied the Eclectroretinographic alterations and the histological lesions after the introduction of foreign bodies of iron and copper into the vitreous body of eyes of rabbits. The ERG alterations depend on the kind of the intraocular foreign body and on the size and the time it remained into the eye. These alterations are characterised either by a parallel diminution of the a and b wave of the ERG, or by an increase of the a wave while the b wave becomes flat. From the histological studies it was found that the iron is deposited into the nucleus and the cytoplasm in the form of granules, while the copper causes a violent inflammatory reaction and is deposited extracellularly.