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. 1992 Dec;66(12):7585-8.
doi: 10.1128/JVI.66.12.7585-7588.1992.

Effects of altering palmitylation sites on biosynthesis and function of the influenza virus hemagglutinin

H Y Naim  1 , B Amarneh, N T Ktistakis, M G Roth
Affiliations

Effects of altering palmitylation sites on biosynthesis and function of the influenza virus hemagglutinin

H Y Naim et al. J Virol. 1992 Dec.

Abstract

Mutagenesis studies indicated that the three cytoplasmic cysteines of the influenza virus A/Japan/305/57 hemagglutinin (HA) are all palmitylated, but to an unequal extent. Replacement of all three cysteines abolished palmitylation, but affected neither HA biosynthesis nor function. Palmitate was not required for HA to be incorporated into virions.

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