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Case Reports
. 1977 Aug;29(2):266-71.

Education of lymphocytes in vivo following a transient take of a matched unrelated bone-marrow graft in man

S F Goldmann, T Kristensen, N Grunnet, H P Lohrmann, H Heimpel, F Kissmeyer-Nielsen
Case Reports

Education of lymphocytes in vivo following a transient take of a matched unrelated bone-marrow graft in man

S F Goldmann et al. Clin Exp Immunol. 1977 Aug.

Abstract

A patient suffering from aplastic anaemia was treated by bone-marrow transplantation from an ABO- and HLA-identical, MLC- and CML-negative, unrelated donor. MLC and CML became positive after transplantation indicating that a cellular immune response had developed against lymphocyte determinants not recognized prior to sensitization in vivo. Whether these determinants are governed by genes of the HLA region is unknown at present.

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References

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