doi: 10.1038/359794a0.
A second-generation linkage map of the human genome
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- PMID: 1436057
- DOI: 10.1038/359794a0
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A second-generation linkage map of the human genome
Nature.
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Abstract
A linkage map of the human genome has been constructed based on the segregation analysis of 814 newly characterized polymorphic loci containing short tracts of (C-A)n repeats in a panel of DNAs from eight large families. Statistical linkage analysis placed 813 of the markers into 23 linkage groups corresponding to the 22 autosomes and the X chromosome; 605 show a heterozygosity above 0.7 and 553 could be ordered with odds ratios above 1,000:1. The distance spanned corresponds to approximately 90% of the estimated length of the human genome.
Comment in
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Human genome project. Variation is now the theme.Nature. 1992 Oct 29;359(6398):777-8. doi: 10.1038/359777a0. Nature. 1992. PMID: 1359422 No abstract available.
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