Variations in the length of S-phase related to the time cells are blocked at the G1-S interface
- PMID: 144048
- DOI: 10.1007/BF00292940
Variations in the length of S-phase related to the time cells are blocked at the G1-S interface
Abstract
The inhibition of DNA synthesis with hydroxyurea or 5-fluorode-oxyuridine decreases the duration of S-phase of synchronously growing Chinese hamster cultures. - The observed drug effects are discussed in relation to an alteration of programmed DNA replication.