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. 1992 Sep-Oct;12(5):1757-9.

Influence of radiation treatment on serum transferrin and tumor necrosis factor-alpha

B Agroyannis  1 , J Kouvaris, H Tzanatos, K Chondros, E Stringou, A Damatopoulou, A Dalamangas, D Koutsikos, C Papavasiliou
Affiliations
  • PMID: 1444242

Influence of radiation treatment on serum transferrin and tumor necrosis factor-alpha

B Agroyannis et al. Anticancer Res. 1992 Sep-Oct.

Abstract

This study deals with the effect of radiation treatment (RT) on serum transferrin and tumor necrosis factor-alpha (TNF-alpha) in patients with malignant tumors. In 21 patients who received 36-60 Gy in 20 to 30 sessions of RT, serum transferrin and TNF-alpha were determined pre-RT, after 10 to 15 sessions (middle of RT) and after 20 to 30 sessions (end of RT). The values of serum transferrin pre-RT were significantly higher than those in the middle and at the end of RT (p < 0.001). The values of TNF-alpha were increased by RT and were significantly higher at the end of RT as compared to the pre-RT values (p < 0.05). The values of serum transferrin and TNF-alpha show a tendency to negative correlation, either as a whole or separately pre- and under-RT. However, no correlation was statistically significant.

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