Is a trypsin-like protease of mites a Der f III allergen?
Affiliations
- PMID: 1444822
Item in Clipboard
Is a trypsin-like protease of mites a Der f III allergen?
Arerugi.
1992 Jun.
Abstract
A trypsin-like protease was purified from mite (Dermatophagoides farinae) fecal extract. In SDS-PAGE, the mite trypsin-like protease showed a single band at 34 kD. The purified trypsin-like protease possessed potent allergenic activity. Both the twenty N-terminal amino acid sequence and the amino acid composition of the purified protease were very similar to those of Der f III. These data strongly suggest that the trypsin-like protease in the mite is a Der f III allergen.
Similar articles
-
The group III allergen from the house dust mite Dermatophagoides pteronyssinus is a trypsin-like enzyme.Immunology. 1992 Jan;75(1):29-35. Immunology. 1992. PMID: 1537598 Free PMC article.
-
Trypsin-like protease of mites: purification and characterization of trypsin-like protease from mite faecal extract Dermatophagoides farinae. Relationship between trypsin-like protease and Der f III.Clin Exp Allergy. 1993 Sep;23(9):777-84. doi: 10.1111/j.1365-2222.1993.tb00366.x. Clin Exp Allergy. 1993. PMID: 10779309
-
[Allergens from Dermatophagoides dust mites: origin, antigenic and structural characteristics, and therapeutic agents].Biokhimiia. 1995 Feb;60(2):218-37. Biokhimiia. 1995. PMID: 7718666 Review. Russian.
-
Antigen Der f I from the dust mite Dermatophagoides farinae: structural comparison with Der p I from Dermatophagoides pteronyssinus and epitope specificity of murine IgG and human IgE antibodies.J Immunol. 1986 Nov 1;137(9):2841-7. J Immunol. 1986. PMID: 2428875
-
On the potential significance of the enzymatic activity of mite allergens to immunogenicity. Clues to structure and function revealed by molecular characterization.Clin Exp Allergy. 1997 Jan;27(1):10-21. Clin Exp Allergy. 1997. PMID: 9117873 Review. No abstract available.
Cited by
-
Dust mite allergens.Clin Rev Allergy Immunol. 1995 Summer;13(2):135-50. doi: 10.1007/BF02758098. Clin Rev Allergy Immunol. 1995. PMID: 7489260 Review. No abstract available.
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources