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. 1992;2(6):411-3.
doi: 10.3109/10425179209020821.

Nucleotide sequence of bovine interleukin-6 cDNA

L Droogmans  1 , I Cludts, Y Cleuter, R Kettmann, A Burny
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Nucleotide sequence of bovine interleukin-6 cDNA

L Droogmans et al. DNA Seq. 1992.

Abstract

We report the cloning of bovine interleukin-6 (IL-6) cDNA. The clone was isolated from a bovine-leukemia virus (BLV)-induced B cell-lymphosarcoma cDNA library cloned in the bacteriophage lambda gt11. The cDNA encodes a full length IL-6 protein made of 208 amino acids with 65, 53, 42 and 42% homology to published sequences of porcine, human, mouse and rat IL-6, respectively. The significance of IL-6 expression in a BLV-induced tumor is briefly discussed.

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