Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comparative Study
. 1992 Oct 7;115(2):143-7.
doi: 10.1007/BF00230324.

Effect of ethanol on hepatic ribosomal proteins and mRNA

K S Haviryaji  1 , R Srinivas, T Suryanarayana, M C Vemuri
Affiliations
Comparative Study

Effect of ethanol on hepatic ribosomal proteins and mRNA

K S Haviryaji et al. Mol Cell Biochem. .

Abstract

Levels of RNA, mRNA and separation of ribosomal proteins from control and ethanol treated rat liver, showed no change in total RNA content, but poly(A+)mRNA was reduced significantly in ethanolic rats. Ribosomal proteins S2, S3a, S3b, S4, L3, L4, L4a, L10a and L15 were found substantially reduced in experimental rat livers. This study suggests decrease in poly(A+) mRNA coupled with loss of ribosomal proteins must be responsible for decreased protein synthesis in chronic alcoholism.

PubMed Disclaimer

References

    1. Membr Biochem. 1990 Jul-Sep;9(3):227-37 - PubMed
    1. Biochem Int. 1990;20(3):573-7 - PubMed
    1. Eur J Biochem. 1990 Jul 20;191(1):1-17 - PubMed
    1. Biochim Biophys Acta. 1977 Jan 20;474(2):312-20 - PubMed
    1. J Neurosci Res. 1978;3(5-6):375-87 - PubMed

Publication types

LinkOut - more resources