Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1992 Nov;43(3):949-51.
doi: 10.1016/0091-3057(92)90430-n.

Effect of oxiracetam on scopolamine-induced amnesia in the rat in a spatial learning task

N Pitsikas  1 , S Algeri
Affiliations

Effect of oxiracetam on scopolamine-induced amnesia in the rat in a spatial learning task

N Pitsikas et al. Pharmacol Biochem Behav. 1992 Nov.

Abstract

The effects of the nootropic agent 4-hydroxy-2-oxopyrrolidinoacetamide (oxiracetam) on memory and performance impairments induced by scopolamine were evaluated in the Morris water maze task. No effect was seen on the performance of rats when treated with oxiracetam (30 mg/kg, IP) alone. Task performance of scopolamine (0.2 mg/kg, SC)-treated rats was impaired as compared to that of control animals. The behavioral deficits expressed in the task by scopolamine treatment were attenuated by the same dose of oxiracetam.

PubMed Disclaimer

Publication types

LinkOut - more resources