Defining control: regulation of dendritic cell activation and immune homeostasis by SOCS1
- PMID: 14499106
- DOI: 10.1016/s1074-7613(03)00243-7
Defining control: regulation of dendritic cell activation and immune homeostasis by SOCS1
Abstract
SOCS1 is a key regulator of cytokine signaling and is important for maintaining balance in the immune system. In addition to roles in T, NKT, and macrophage cell function, a new study indicates that SOCS1 modulates dendritic cell activation and may help prevent autoimmunity.
Comment on
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Suppressor of cytokine signaling-1 is essential for suppressing dendritic cell activation and systemic autoimmunity.Immunity. 2003 Sep;19(3):437-50. doi: 10.1016/s1074-7613(03)00240-1. Immunity. 2003. PMID: 14499118
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