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Comparative Study
. 2003 Sep;89(3):214-26.
doi: 10.1007/s00422-003-0422-x. Epub 2003 Jul 31.

Biophysical model of synaptic plasticity dynamics

Henry D I Abarbanel  1 , Leif Gibb, R Huerta, M I Rabinovich
Affiliations
Comparative Study

Biophysical model of synaptic plasticity dynamics

Henry D I Abarbanel et al. Biol Cybern. 2003 Sep.

Abstract

We discuss a biophysical model of synaptic plasticity that provides a unified view of the outcomes of synaptic modification protocols, including: (1) prescribed time courses of postsynaptic intracellular Ca(2+) release, (2) postsynaptic voltage clamping with presentation of presynaptic spike trains at various frequencies, (3) direct postsynaptic response to presynaptic spike trains at various frequencies, and (4) LTP/LTD as a response to precisely timed presynaptic and postsynaptic spikes.

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