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. 2003 Oct;47(10):3336-8.
doi: 10.1128/AAC.47.10.3336-3338.2003.

PCR and restriction endonuclease assay for detection of a novel mutation associated with sulfonamide resistance in Neisseria meningitidis

Désirée E Bennett  1 , Mary T Cafferkey
Affiliations

PCR and restriction endonuclease assay for detection of a novel mutation associated with sulfonamide resistance in Neisseria meningitidis

Désirée E Bennett et al. Antimicrob Agents Chemother. 2003 Oct.

Abstract

We identified a previously undocumented mutation in the dihydropteroate synthase (folP) gene associated with Neisseria meningitidis sulfonamide resistance. A PCR-based assay to detect this mutation, which is 100% predictive of sulfonamide resistance, was developed.

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References

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