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Clinical Trial
. 2003 May:30 Suppl 2:S94-6.

[Comparative effectiveness of flupenthixol and risperidone on negative symptoms of schizophrenia]

[Article in German]
Michael Philipp  1 , Otto M Lesch, Max Schmauss, Matthias Dose, Thomas Glaser
Affiliations
  • PMID: 14509050
Clinical Trial

[Comparative effectiveness of flupenthixol and risperidone on negative symptoms of schizophrenia]

[Article in German]
Michael Philipp et al. Psychiatr Prax. 2003 May.

Abstract

The efficacy of flupentixol and risperidone were compared in a randomized double-blind study in 153 chronic schizophrenic patients. Flupentixol showed to be not inferior to risperidone concerning schizophrenic negative symptoms at week 8, 16 and 24. Positive symptoms and general psychopathology improved comparably, too. There was a trend in favor of flupentixol concerning the improvement of depressive symptoms and a trend in favor of risperidone concerning the improvement of preexisting parkinsonian symptoms. The study data justify to regard flupentixol as a "partial atypical" antipsychotic.

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