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Comment
. 2003 Sep 20;327(7416):681-2; author reply 682.
doi: 10.1136/bmj.327.7416.681-c.

Conundrum of the HOPE study: time of taking ramipril may account for lack of relation between blood pressure and outcome

Roy Taylor
Comment

Conundrum of the HOPE study: time of taking ramipril may account for lack of relation between blood pressure and outcome

Roy Taylor. BMJ. .
No abstract available

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Comment in

Comment on

  • Use of ramipril in preventing stroke: double blind randomised trial.
    Bosch J, Yusuf S, Pogue J, Sleight P, Lonn E, Rangoonwala B, Davies R, Ostergren J, Probstfield J; HOPE Investigators. Heart outcomes prevention evaluation. Bosch J, et al. BMJ. 2002 Mar 23;324(7339):699-702. doi: 10.1136/bmj.324.7339.699. BMJ. 2002. PMID: 11909785 Free PMC article. Clinical Trial.

References

    1. HOPE Investigators. Effects of an angiotensin-converting enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients. N Engl J Med 2000;342: 145-53. - PubMed
    1. Sleight P, Yusuf S, Pogue J, Psuyuki R, Probstfield J. Blood pressure reduction and cardiovascular risk in HOPE study. Lancet 2001;358: 2130-1. - PubMed
    1. Bosch J, Yusuf S, Pogue J, Sleight P, Lonn E, Rangoonwala B, et al. Effect of ramipril in preventing stroke: double blind randomised trial. BMJ 2002;324: 699-702. - PMC - PubMed
    1. Svensson P, de Faire U, Sleight P, Yusuf S, Ostergren J. Comparative effects of ramipril on ambulatory and office blood pressures: a HOPE substudy. Hypertension 2001;38: e28-32. - PubMed
    1. Sleight P, Pogue J, Yusef S. Blood pressure and cardiovascular risk in the HOPE study. Author's reply. Lancet 2002;359: 2118. - PubMed

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