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. 2003 Oct;29(8):682-8.
doi: 10.1016/s0748-7983(03)00149-5.

Pseudomyxoma peritonei: a review of 62 cases

S van Ruth  1 , Y I Z Acherman, M J van de Vijver, A A M Hart, V J Verwaal, F A N Zoetmulder
Affiliations

Pseudomyxoma peritonei: a review of 62 cases

S van Ruth et al. Eur J Surg Oncol. 2003 Oct.

Abstract

Aim: Pseudomyxoma peritonei (PMP) is a rare disease characterized by the abundance of mucus in the abdomen without extra-peritoneal growth.

Methods: Our patients with PMP have been treated with cytoreduction and hyperthermic intraperitoneal chemotherapy since 1996. The clinical and histopathological features of PMP and the relation of these features with disease-free interval and survival were assessed.

Results: Sixty-two patients with PMP (24 M/38 F) were studied. Adenomatous mucosal changes were present in 31 patients. In females, the ovaries were normal in 5 patients and pseudomyxoma ovarii was present in 20 patients. Patients with minimal atypia and with 1% focal proliferation or less (n=38) had a better survival (p=0.0008) than those with more focal proliferation (n=14).

Conclusion: In most patients with PMP the appendix is affected; in females the ovaries are usually also involved. Focal proliferation appears to be a prognostic factor.

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