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. 2003 Aug;9(5):350-1, 354.

[Infection of Chlamydia trachomatis and apoptosis of spermatogenic cells]

[Article in Chinese]
Chang-Chun Wan  1 , Hong Wang, Bao-Jin Hao, Xue-Jun Shang, Yu-Feng Huang
Affiliations
  • PMID: 14513642

[Infection of Chlamydia trachomatis and apoptosis of spermatogenic cells]

[Article in Chinese]
Chang-Chun Wan et al. Zhonghua Nan Ke Xue. 2003 Aug.

Abstract

Objective: To evaluate the relationship between infection of Chlamydia Trachomatis(Ct) and apoptosis of spermatogenic cells.

Methods: Apoptotic spermatogenic cells were examined by Wright-Giemsa staining and the terminal deoxynucleotidyl transferase-mediated deoxyuridine triphosphate(dUTP)-biotin nick-end labeling(TUNEL) technique.

Results: Apoptosis rate of Ct infective group was significantly higher than that of normal group(P < 0.01).

Conclusions: Ct infection may cause the apoptosis of spermatogenic cells, which affords an objective evidence for illustrating the mechanism of Ct-infection-induced male infertility.

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