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Review
. 2003;50(3):625-45.

Structure and functions of tumor necrosis factor-alpha converting enzyme

Renata Mezyk  1 , Monika Bzowska, Joanna Bereta
Affiliations
  • PMID: 14515145
Review

Structure and functions of tumor necrosis factor-alpha converting enzyme

Renata Mezyk et al. Acta Biochim Pol. 2003.

Abstract

Tumor necrosis factor-alpha converting enzyme (TACE) is the first described and best characterized secretase. In this review the structure and the possible roles for TACE are summarized. The substrate specificity and the regulation of TACE activity as well as redundancy and possible cooperations of distinct secretases are also discussed.

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