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Review
. 2003;4(10):119.
doi: 10.1186/gb-2003-4-10-119. Epub 2003 Sep 19.

New methods for finding disease-susceptibility genes: impact and potential

Mark I McCarthy  1 , Damian Smedley, Winston Hide
Affiliations
Review

New methods for finding disease-susceptibility genes: impact and potential

Mark I McCarthy et al. Genome Biol. 2003.

Abstract

Improved techniques for defining disease-gene location and evaluating the biological candidacy of regional transcripts will hasten disease-gene discovery.

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Figures

Figure 1
Figure 1
Candidate-gene identification past and present. In the past, the emphasis was on using linkage analysis to direct positional-cloning efforts, and on the application of our limited understanding of disease pathogenesis to select biologically relevant candidate genes. Now, additional techniques are providing new routes to the identification of disease-susceptibility genes. See text for further details.
See this image and copyright information in PMC

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