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. 2003 Sep;9(9):1168-9.
doi: 10.3201/eid0909.020666.

Co-trimoxazole-sensitive, methicillin-resistant Staphylococcus aureus, Israel, 1988-1997

Jihad Bishara  1 , Silvio Pitlik, Zmira Samra, Itzhak Levy, Mical Paul, Leonard Leibovici
Affiliations

Co-trimoxazole-sensitive, methicillin-resistant Staphylococcus aureus, Israel, 1988-1997

Jihad Bishara et al. Emerg Infect Dis. 2003 Sep.

Abstract

Among bloodstream methicillin-resistant Staphylococcus aureus (MRSA) isolates from adult patients in a single hospital, susceptibility to co-trimoxazole increased progressively from 31% in 1988 to 92% in 1997 (p<0.0001). If also observed in other institutions, these findings should encourage the performance of a clinical trial of sufficient size to compare co-trimoxazole to vancomycin in treating MRSA infections.

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Figure
Figure
Co-trimoxazole susceptibility among methicillin-resistant Staphylococcus aureus. Columns indicate percentage of hospital-acquired methicillin-resistant Staphylococcus aureus (MRSA) susceptible to co-trimoxazole. Numbers on top of the columns are absolute numbers of hospital-acquired MRSA susceptible to co-trimoxazole.
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