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. 1992 Dec;60(12):5291-3.
doi: 10.1128/iai.60.12.5291-5293.1992.

An 87-kilodalton glucan-binding protein of Streptococcus sobrinus B13

C D Wu-Yuan  1 , R E Gill
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An 87-kilodalton glucan-binding protein of Streptococcus sobrinus B13

C D Wu-Yuan et al. Infect Immun. 1992 Dec.

Abstract

An 87-kDa glucan-binding protein (GBP) of Streptococcus sobrinus B13 (serotype d) was isolated and purified from extracellular culture supernatant by using affinity chromatography on Sephadex G-50 and elution with a guanidine HCl gradient. Western blot (immunoblot) analysis showed it to be antigenically related, but not completely identical, to the 74-kDa GBP of Streptococcus mutans Ingbritt. The 87-kDa GBP has no glucosyltransferase activity. A possible role for this GBP in the cariogenicity of S. sobrinus B13 is suggested.

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