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. 2003 Sep;189(3):813-7.
doi: 10.1067/s0002-9378(03)00658-6.

Antenatal factors associated with significant birth weight discordancy in twin gestations

Vctor H González-Quintero  1 , Barbara Luke, Mary J O'sullivan, Ruta Misiunas, Elaine Anderson, Clark Nugent, Frank Witter, Jill Mauldin, Roger Newman, Mary D'alton, David Grainger, George Saade, Gary Hankins, George Macones
Affiliations

Antenatal factors associated with significant birth weight discordancy in twin gestations

Vctor H González-Quintero et al. Am J Obstet Gynecol. 2003 Sep.

Abstract

Objective: The purpose of this study was to evaluate factors that are associated with significant birth weight discordancy.

Study design: As a part of an ongoing collaborative study of twins, maternal and fetal data were obtained from the medical records of twin gestations at eight medical centers. The study population was divided into groups by difference in birth weight discordancy (>or=20%, >or=25%, and >or=30%)

Results: Severe birth weight discordancy was associated with fetal growth deceleration by 20 to 28 weeks (adjusted odds ratio, 4.90; 95% CI, 3.15-7.64) and between 28 weeks to birth (adjusted odds ratio, 3.48; 95% CI, 1.72-7.06). Antenatal bleeding (adjusted odds ratio, 1.86; 95% CI, 1.08-3.21), preeclampsia (adjusted odds ratio, 1.70, 95% CI, 1.21-2.41), and monochorionicity (adjusted odds ratio, 2.35, 95% CI, 11.71-3.23) were also associated with birth weight discordancy.

Conclusion: These data demonstrate the importance of the early diagnosis of placental chorionicity, because monochorionicity is associated with a 2-fold increase in birth weight discordancy in twin gestations.

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