Comparison of cytobrushes with swabs for recovery of endocervical cells and for Chlamydiazyme detection of Chlamydia trachomatis
- PMID: 1452671
- PMCID: PMC270565
- DOI: 10.1128/jcm.30.11.2988-2990.1992
Comparison of cytobrushes with swabs for recovery of endocervical cells and for Chlamydiazyme detection of Chlamydia trachomatis
Abstract
Endocervical swab and cytobrush specimens from 1,301 symptomatic women were microscopically analyzed for adequacy and tested using Chlamydiazyme (CZ) (Abbott Laboratories). When the swab specimen was collected first, blocking antibody-confirmed CZ-positive results were obtained from 48 (8.0%) of 599 patients, 42 (87.5%) from swabs and 46 (95.8%) from cytobrushes (not significant). When the swab specimen was collected second, confirmed CZ-positive results were obtained from 46 (6.6%) of 702 patients, 44 (95.6%) from swabs and 41 (89.1%) from cytobrushes (not significant). Cytobrushes offered no significant advantage over swabs for CZ detection of Chlamydia trachomatis.
Similar articles
-
Effect of endocervical specimen quality on detection of Chlamydia trachomatis and on the incidence of false-positive results with the Chlamydiazyme method.J Clin Microbiol. 1990 Jun;28(6):1108-13. doi: 10.1128/jcm.28.6.1108-1113.1990. J Clin Microbiol. 1990. PMID: 2199483 Free PMC article.
-
Efficacy of duplicate genital specimens and repeated testing for confirming positive results for chlamydiazyme detection of Chlamydia trachomatis antigen.J Clin Microbiol. 1989 Jun;27(6):1218-21. doi: 10.1128/jcm.27.6.1218-1221.1989. J Clin Microbiol. 1989. PMID: 2753999 Free PMC article.
-
Comparison of the Clearview Chlamydia test, Chlamydiazyme, and cell culture for detection of Chlamydia trachomatis in women with a low prevalence of infection.J Clin Microbiol. 1991 Sep;29(9):2086-8. doi: 10.1128/jcm.29.9.2086-2088.1991. J Clin Microbiol. 1991. PMID: 1774342 Free PMC article.
-
Evaluation of two ELISA's for detecting Chlamydia trachomatis from endocervical swabs.Diagn Microbiol Infect Dis. 1992 Sep-Oct;15(7):579-86. doi: 10.1016/0732-8893(90)90034-s. Diagn Microbiol Infect Dis. 1992. PMID: 1424514
-
Detection of Neisseria gonorrhoeae and Chlamydia trachomatis in genitourinary specimens from men and women by a coamplification PCR assay.J Clin Microbiol. 1997 Jun;35(6):1536-40. doi: 10.1128/jcm.35.6.1536-1540.1997. J Clin Microbiol. 1997. PMID: 9163477 Free PMC article.
Cited by
-
Current methods of laboratory diagnosis of Chlamydia trachomatis infections.Clin Microbiol Rev. 1997 Jan;10(1):160-84. doi: 10.1128/CMR.10.1.160. Clin Microbiol Rev. 1997. PMID: 8993862 Free PMC article. Review.
-
Assessment of self taken swabs versus clinician taken swab cultures for diagnosing gonorrhoea in women: single centre, diagnostic accuracy study.BMJ. 2012 Dec 12;345:e8107. doi: 10.1136/bmj.e8107. BMJ. 2012. PMID: 23236033 Free PMC article.
-
Cervical sampling for diagnosis of genital chlamydial infection with a new brush device.Genitourin Med. 1993 Oct;69(5):397-9. doi: 10.1136/sti.69.5.397. Genitourin Med. 1993. PMID: 8244362 Free PMC article.
-
Assessment of best single sample for finding chlamydia in women with and without symptoms: a diagnostic test study.BMJ. 2012 Dec 12;345:e8013. doi: 10.1136/bmj.e8013. BMJ. 2012. PMID: 23236032 Free PMC article. Clinical Trial.
References
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources