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Review
. 2003 Sep;17(3):443-9.
doi: 10.1016/s1521-6896(02)00091-5.

Spinal anaesthesia and the use of anticoagulants

Affiliations
Review

Spinal anaesthesia and the use of anticoagulants

Patrick Narchi. Best Pract Res Clin Anaesthesiol. 2003 Sep.

Abstract

This chapter addresses the increasing incidence of spinal haematoma after central neuraxis anaesthesia in patients receiving drugs that affect coagulation. Administration of low-molecular-weight heparins in the perioperative period is highlighted because these drugs remain the 'gold standard' for prophylaxis against deep-vein thrombosis. The performance of spinal anaesthesia in patients already receiving antiplatelet drugs is discussed--as well as special warnings in such a setting. In addition, issues such as those concerning the administration of unfractionated heparin, anti-vitamin K drugs or new antiplatelet and antithrombotic medications are addressed. Finally, specific recommendations regarding each class of drug are defined in order to avoid the occurrence of a rare but catastrophic event such as spinal haematoma.

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