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Review
. 2003 Nov;62 Suppl 2(Suppl 2):ii60-7.
doi: 10.1136/ard.62.suppl_2.ii60.

Angiogenesis as a target in rheumatoid arthritis

Affiliations
Review

Angiogenesis as a target in rheumatoid arthritis

A E Koch. Ann Rheum Dis. 2003 Nov.
No abstract available

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Figures

Figure 1
Figure 1
Schematic diagram of the Matrigel angiogenesis in vivo assay.
Figure 2
Figure 2
Suggested mechanism of the soluble 4A11 antigen (Ley/H). Endothelial cells are activated by inflammatory mediators to produce the 4A11 antigen, which is then secreted to mediate angiogenesis in adjacent endothelial cells. This is the same paradigm for soluble molecules such as CD146, soluble E-selectin, or soluble VCAM-1.
Figure 3
Figure 3
Balance of angiogenesis inducers and angiogenesis inhibitors in pathological disease states.

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