Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2003 Oct;41(10):4898-900.
doi: 10.1128/JCM.41.10.4898-4900.2003.

Successful outcome of disseminated Fusarium infection with skin localization treated with voriconazole and amphotericin B-lipid complex in a patient with acute leukemia

Isabelle Durand-Joly  1 , Serge Alfandari, Zinnédine Benchikh, Marion Rodrigue, Ana Espinel-Ingroff, Benoit Catteau, Christophe Cordevant, Daniel Camus, Eduardo Dei-Cas, Francis Bauters, Laurence Delhaes, Stéphane De Botton
Affiliations
Case Reports

Successful outcome of disseminated Fusarium infection with skin localization treated with voriconazole and amphotericin B-lipid complex in a patient with acute leukemia

Isabelle Durand-Joly et al. J Clin Microbiol. 2003 Oct.

Abstract

A disseminated Fusarium oxysporum infection with skin localization was diagnosed in a woman with a relapse of B-acute leukemia during induction chemotherapy. The infection was refractory to amphotericin B-lipid complex alone but responded successfully when voriconazole was added.

PubMed Disclaimer

Figures

FIG. 1.
FIG. 1.
Disseminated fusariosis infection. The patient presented multiple skin varicelliform lesions on the face (left) and on the leg (right). A close-up view of a necrotic lesion (inset) shows more detail.
See this image and copyright information in PMC

References

    1. Anaissie, E., H. Kantarjian, P. Jones, B. Barlogie, M. Luna, G. Lopez-Berestein, and G. P. Bodey. 1986. Fusarium. A newly recognized fungal pathogen in immunosuppressed patients. Cancer 57:2141-2145. - PubMed
    1. Arikan, S., M. Lozano-Chiu, V. Paetznick, S. Nangia, and J. H. Rex. 1999. Microdilution susceptibility testing of amphotericin B, itraconazole, and voriconazole against clinical isolates of Aspergillus and Fusarium species. J. Clin. Microbiol. 37:3946-39451. - PMC - PubMed
    1. Boutati, E. I., and E. J. Anaissie. 1997. Fusarium, a significant emerging pathogen in patients with hematologic malignancy: ten years' experience at a cancer center and implications for management. Blood 90:999-1008. - PubMed
    1. Dei-Cas, E., L. Dujardin, M. E. Ribeiro Pinto, F. Ajana, J. Fruit, D. Poulain, D. Camus, and A. Vernes. 1991. Kinetic study of antifungal activity of amphotericin B, 5-fluorocytosine and ketoconazole against clinical yeast isolates using liquid-phase turbidimetry. Mycoses 34:167-172. - PubMed
    1. Denning, D. W., P. Ribaud, N. Milpied, D. Caillot, R. Herbrecht, E. Thiel, A. Haas, M. Ruhnke, and H. Lode. 2002. Efficacy and safety of voriconazole in the treatment of acute invasive aspergillosis. Clin. Infect. Dis. 34:563-571. - PubMed

Publication types

LinkOut - more resources