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Review
. 1992 Nov;17(11):463-8.
doi: 10.1016/0968-0004(92)90489-v.

The ATP-dependent glutathione S-conjugate export pump

T Ishikawa  1
Affiliations
Review

The ATP-dependent glutathione S-conjugate export pump

T Ishikawa. Trends Biochem Sci. 1992 Nov.

Abstract

The ATP-dependent glutathione S-conjugate export pump (GS-X pump) plays a physiologically important role as a member of the 'phase III' system in xenobiotic metabolism as well as in the release of biologically active endogenous substances from cells. In addition, this export pump is potentially involved in the modulation of the antiproliferative action of certain antitumor agents.

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Comment in

  • Phase III detoxification system.
    Zimniak P, Awasthi S, Awasthi YC. Zimniak P, et al. Trends Biochem Sci. 1993 May;18(5):164-6. doi: 10.1016/0968-0004(93)90106-w. Trends Biochem Sci. 1993. PMID: 8101022 No abstract available.

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