Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2003;18(9):845-54.
doi: 10.1023/a:1025643303914.

Epidemiology of age-related maculopathy: a review

Redmer van Leeuwen  1 , Caroline C W Klaver, Johannes R Vingerling, Albert Hofman, Paulus T V M de Jong
Affiliations
Review

Epidemiology of age-related maculopathy: a review

Redmer van Leeuwen et al. Eur J Epidemiol. 2003.

Abstract

Age-related maculopathy (ARM) is a degenerative disease of the retina and the leading cause of incurable blindness and visual impairment in industrialized countries. By definition, ARM is confined to the age-category above 50 years. The aetiology of ARM is still unknown, despite intensive research on many fronts. In this paper, we provide a review of the epidemiology of ARM. The most prominent findings were an exponential increase in frequency with age, a significant familial and genetic component, and a strong association with smoking. Other risk factors that were found less consistently were atherosclerosis, low intake of antioxidant nutrients, and cataract extraction. Future studies, both observational and experimental, will hopefully identify more risk factors that are amenable to prevention.

PubMed Disclaimer

References

    1. Arch Ophthalmol. 1993 Jan;111(1):104-9 - PubMed
    1. Ophthalmology. 2003 Jan;110(1):25-33 - PubMed
    1. Ophthalmic Epidemiol. 2001 Sep;8(4):237-49 - PubMed
    1. Arch Ophthalmol. 1988 Feb;106(2):192-8 - PubMed
    1. Surv Ophthalmol. 2000 Sep-Oct;45(2):115-34 - PubMed

Publication types