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. 1992 Sep;37(1-2):155-6.
doi: 10.1007/BF01987905.

The effect of hyaluronan on interleukin-1 alpha-induced prostaglandin E2 production in human osteoarthritic synovial cells

T Yasui  1 , M Akatsuka, K Tobetto, M Hayaishi, T Ando
Affiliations

The effect of hyaluronan on interleukin-1 alpha-induced prostaglandin E2 production in human osteoarthritic synovial cells

T Yasui et al. Agents Actions. 1992 Sep.

Abstract

An in vitro study on the effects of hyaluronan (HA) on interleukin-1 alpha-induced prostaglandin E2 (PGE2) production in human osteoarthritic synovial cells indicated that PGE2 induction was suppressed by HA in a dose- and molecular weight-dependent manner.

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