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Review
. 2003 Jun;15(3):125-33.
doi: 10.1016/s1044-5323(03)00032-0.

Cell death during lymphocyte development and activation

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Review

Cell death during lymphocyte development and activation

Ignacio Moreno de Alborán et al. Semin Immunol. 2003 Jun.

Abstract

The development and homeostasis of the immune system requires an exquisite balance between cell proliferation and cell death. In this review, we discuss several in vivo and in vitro models that have been developed to help understand the importance of apoptosis during B and T cell development and activation.

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