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Review
. 2003 May-Jun;49(3):250-62.

[Antioxidants in malignant neoplasms in humans and animals]

[Article in Russian]
N V Nikiforova  1 , A E Berman
Affiliations
  • PMID: 14564734
Review

[Antioxidants in malignant neoplasms in humans and animals]

[Article in Russian]
N V Nikiforova et al. Biomed Khim. 2003 May-Jun.

Abstract

This review is devoted to the role of low molecular weight antioxidants and antioxidant enzymes in cancerogenesis. The data on accumulation of lipid-soluble and water-soluble antioxidants in a number of malignant human and experimental tumors especially in the renal cell carcinoma tissues are analyzed. A possibility is discussed concerning the pro- and anticarcinogenic effects of the abundant tumor content of antioxidants. Implication of antioxidants in tumor resistance to chemotherapeutic drugs and ionizing radiation is discussed.

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