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Clinical Trial
. 2003;49(4):464-6.

[Anticytosine therapy for primary myelodysplastic syndrome]

[Article in Russian]
K M Abdulkadyrov  1 , S V Gritsaev, S S Bessmel'tsev, I S Martynkevich, S A Tiranova, M N Blinov, R I Osipova
Affiliations
  • PMID: 14569938
Clinical Trial

[Anticytosine therapy for primary myelodysplastic syndrome]

[Article in Russian]
K M Abdulkadyrov et al. Vopr Onkol. 2003.

Abstract

A pilot study of anticytocine therapy (PCD) was carried out in 9 patients with primary myelodysplastic syndrome (MDS). After 12 weeks, 2 patients (22%) showed hematological response cutting down the need for washed-out erythrocyte transfusions by half or more. MDS progression at different stages was reported in 4; transformation to acute myeloleukemia--2. PCD treatment is indicated in MDS patients, aged over 65, with a less than 10% blast level of the bone marrow, and without any risks of tumor progression.

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