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Review
. 2003 Oct;4(10):767-76.
doi: 10.1038/nrm1229.

Ras GTPases: integrins' friends or foes?

Kayoko Kinbara  1 , Lawrence E Goldfinger, Malene Hansen, Fan-Li Chou, Mark H Ginsberg
Affiliations
Review

Ras GTPases: integrins' friends or foes?

Kayoko Kinbara et al. Nat Rev Mol Cell Biol. 2003 Oct.

Erratum in

  • Nat Rev Mol Cell Biol. 2004 Jan;5(1):75

Abstract

Integrins are cell-surface receptors that mediate and coordinate cellular responses to the extracellular matrix (ECM). Cellular signalling pathways can regulate cell adhesion by altering the affinity and avidity of integrins for ECM. The Ras family of small G proteins, which includes H-ras, R-ras and Rap, are important elements in cellular signalling pathways that control integrin function.

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