A function for subtelomeric DNA in Saccharomyces cerevisiae
- PMID: 14573499
- PMCID: PMC1462788
- DOI: 10.1093/genetics/165.2.929
A function for subtelomeric DNA in Saccharomyces cerevisiae
Abstract
The subtelomeric DNA sequences from chromosome I of Saccharomyces cerevisiae are shown to be inherently poor substrates for meiotic recombination. On the basis of these results and prior observations that crossovers near telomeres do not promote efficient meiosis I segregation, we suggest that subtelomeric sequences evolved to prevent recombination from occurring where it cannot promote efficient segregation.
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