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. 1992 Nov;65(5):201-5.
doi: 10.1007/BF01703945.

The BFM-protocol for HIV-negative Burkitt's lymphomas and L3 ALL in adult patients: a high chance for cure

H W Pees  1 , H Radtke, J Schwamborn, N Graf
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The BFM-protocol for HIV-negative Burkitt's lymphomas and L3 ALL in adult patients: a high chance for cure

H W Pees et al. Ann Hematol. 1992 Nov.

Abstract

During a period of 9 years we used the pediatric BFM-NHL protocol for treatment of 14 adult patients with Burkitt's lymphoma or L3 acute lymphoblastic leukemia. Ten of 14 patients obtained a complete remission including 5/8 with stage-IV disease or B-ALL. After a median follow-up of 55 months none of these ten patients relapsed. The projected survival after 8 years is 71%. Toxicity was moderate, with one early death; a tumor lysis syndrome occurred in four patients. From our experience we conclude that the BFM-NHL protocol is very effective in adult patients, with a high cure rate and acceptable toxicity, even in advanced stages of disease.

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References

    1. J Clin Oncol. 1991 Jan;9(1):123-32 - PubMed
    1. Blut. 1986 Oct;53(4):279-86 - PubMed
    1. Am J Med. 1991 Mar;90(3):328-37 - PubMed
    1. J Clin Oncol. 1989 Aug;7(8):1018-26 - PubMed
    1. J Clin Oncol. 1991 Jun;9(6):941-6 - PubMed

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