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Case Reports
. 2003 Nov;49(5 Suppl):S283-5.
doi: 10.1016/s0190-9622(03)00744-8.

Hypocomplementemic urticarial vasculitis with angioedema, a rare presentation of systemic lupus erythematosus: rapid response to rituximab

Kapil Saigal  1 , Isabel C Valencia, Jonathan Cohen, Francisco A Kerdel
Affiliations
Case Reports

Hypocomplementemic urticarial vasculitis with angioedema, a rare presentation of systemic lupus erythematosus: rapid response to rituximab

Kapil Saigal et al. J Am Acad Dermatol. 2003 Nov.

Abstract

We report a case of hypocomplementemic urticarial vasculitis and recurrent angioedema in a patient with systemic lupus erythematosus unresponsive to mycophenolate mofetil, high-dose methylprednisolone, and intravenous immunoglobulin that responded rapidly to rituximab. Rituximab is a monoclonal antibody against CD20 transmembrane protein on the surface of mature and malignant B cells. No adverse effects occurred during or after therapy, and the patient was discharged from the hospital for outpatient rituximab infusion and follow-up care.

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