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. 2003 Dec;17(6):437-40.
doi: 10.1080/1478641031000111516.

Alkaloids from Croton flavens L. and their affinities to GABA-receptors

Wolfram J Eisenreich  1 , Georg Höfner, Franz Bracher
Affiliations

Alkaloids from Croton flavens L. and their affinities to GABA-receptors

Wolfram J Eisenreich et al. Nat Prod Res. 2003 Dec.

Abstract

Phytochemical investigation of several plants of Croton flavens L. from Barbados has led to the isolation of the tetrahydroprotoberberine alkaloids scoulerine and coreximine, as well as the morphinanedienones salutaridine and its racemic form salutarine, sebiferine, norsinoacutine and flavinantine. In a screening for 3H-GABA displacing activity coreximine showed the highest affinity to the GABA(A) receptor.

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