MultiCenter outcome of pediatric oncology patients requiring intensive care
- PMID: 14578035
MultiCenter outcome of pediatric oncology patients requiring intensive care
Abstract
A retrospective cohort study was conducted to evaluate the intensive care outcome of pediatric cancer patients between 1996 and 1998. The study comprised 20 pediatric intensive care units (PICUs) and 802 patients with cancer requiring PICU care. Patients with a history of cancer were identified from PICUs participating in the Pediatric Intensive Care Unit Evaluations program. Their demographics, resource requirements, and outcomes were compared with those of noncancer patients. Cancer patients comprised 3.3% (802/24,431) of PICU admissions. Overall PICU survival was not different between cancer and noncancer patients (95% vs. 96%, p =.2). Cancer patients were older (99 +/- 3 vs. 72 +/- 1 months, p <.001), had similar gender distributions, and had similar lengths of stay (3.3 +/- 0.2 vs. 3.9 +/- 0.1 days, p =.98). The majority (72%) were admitted to the PICU for postoperative care; PICU survival in these patients was 100, 100, and 71% for those not receiving mechanical ventilation or vasoactive agent infusion, those receiving either mechanical ventilation or vasoactive agent infusion, and those receiving both, respectively. PICU survival in nonoperative patients was 87% overall; survival for those requiring ventilation, vasoactive infusions, or both was 93, 89 and 46%. Overall hospital survival was 99% in operative cancer patients and 81% in nonoperative patients (p =.004, operative vs. nonoperative patients). Pediatric cancer patients receiving intensive care do well overall. Outcomes have substantially improved and, in general, the diagnosis of cancer should not limit the provision of intensive care. Additionally, resource use in terms of lengths of stay in the PICU is not different between cancer and noncancer patients.
Similar articles
-
Comparison of critically ill and injured children transferred from referring hospitals versus in-house admissions.Pediatrics. 2008 Apr;121(4):e906-11. doi: 10.1542/peds.2007-2089. Pediatrics. 2008. PMID: 18381519
-
Prognostic factors in pediatric cancer patients admitted to the pediatric intensive care unit.J Pediatr Hematol Oncol. 2009 Jul;31(7):481-4. doi: 10.1097/MPH.0b013e3181a330ef. J Pediatr Hematol Oncol. 2009. PMID: 19564740
-
[Oncology patients in a pediatric intensive care unit--a 7-year experience].Klin Padiatr. 2003 Jul-Aug;215(4):234-40. doi: 10.1055/s-2003-41399. Klin Padiatr. 2003. PMID: 12929015 German.
-
Changes in outcomes (1996-2004) for pediatric oncology and hematopoietic stem cell transplant patients requiring invasive mechanical ventilation.Pediatr Crit Care Med. 2008 May;9(3):270-7. doi: 10.1097/PCC.0b013e31816c7260. Pediatr Crit Care Med. 2008. PMID: 18446105 Review.
-
PICU mortality of children with cancer admitted to pediatric intensive care unit a systematic review and meta-analysis.Crit Rev Oncol Hematol. 2019 Oct;142:153-163. doi: 10.1016/j.critrevonc.2019.07.014. Epub 2019 Aug 3. Crit Rev Oncol Hematol. 2019. PMID: 31404827
Cited by
-
Quality and capacity indicators for hospitalized pediatric oncology patients with critical illness: A modified delphi consensus.Cancer Med. 2020 Oct;9(19):6984-6995. doi: 10.1002/cam4.3351. Epub 2020 Aug 10. Cancer Med. 2020. PMID: 32777172 Free PMC article. Review.
-
Epidemiology and Outcome of Critically Ill Pediatric Cancer and Hematopoietic Stem Cell Transplant Patients Requiring Continuous Renal Replacement Therapy: A Retrospective Nationwide Cohort Study.Crit Care Med. 2019 Nov;47(11):e893-e901. doi: 10.1097/CCM.0000000000003973. Crit Care Med. 2019. PMID: 31464768 Free PMC article.
-
Neurologic Outcomes Following Care in the Pediatric Intensive Care Unit.Curr Treat Options Pediatr. 2017 Sep;3(3):193-207. doi: 10.1007/s40746-017-0092-x. Epub 2017 Jul 26. Curr Treat Options Pediatr. 2017. PMID: 29218262 Free PMC article.
-
Compassionate de-escalation of life-sustaining treatments in pediatric oncology: An opportunity for palliative care and intensive care collaboration.Front Oncol. 2022 Oct 13;12:1017272. doi: 10.3389/fonc.2022.1017272. eCollection 2022. Front Oncol. 2022. PMID: 36313632 Free PMC article.
-
Evaluating the consequences of critically ill patients with pediatric cancer at Aliasghar Children's Hospital.J Family Med Prim Care. 2024 Aug;13(8):3339-3344. doi: 10.4103/jfmpc.jfmpc_1562_23. Epub 2024 Jul 26. J Family Med Prim Care. 2024. PMID: 39228541 Free PMC article.