Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2003 Sep-Oct;2(5):488-94.
doi: 10.1021/pr034020m.

Quantitative metabolome analysis using capillary electrophoresis mass spectrometry

Tomoyoshi Soga  1 , Yoshiaki Ohashi, Yuki Ueno, Hisako Naraoka, Masaru Tomita, Takaaki Nishioka
Affiliations

Quantitative metabolome analysis using capillary electrophoresis mass spectrometry

Tomoyoshi Soga et al. J Proteome Res. 2003 Sep-Oct.

Abstract

A new approach for the comprehensive and quantitative analysis of charged metabolites by capillary electrophoresis mass spectrometry (CE-MS) is proposed. Metabolites are first separated by CE based on charge and size and then selectively detected using MS by monitoring over a large range of m/z values. This method enabled the determination of 352 metabolic standards and its utility was demonstrated in the analysis of 1692 metabolites from Bacillus subtilis extracts, revealing significant changes in metabolites during B. subtilis sporulation.

PubMed Disclaimer

Comment in

Publication types