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Clinical Trial
. 2003 Sep:998:494-9.
doi: 10.1196/annals.1254.064.

Mycophenolate mofetil for myasthenia gravis: a double-blind, placebo-controlled pilot study

Affiliations
Clinical Trial

Mycophenolate mofetil for myasthenia gravis: a double-blind, placebo-controlled pilot study

Matthew N Meriggioli et al. Ann N Y Acad Sci. 2003 Sep.

Abstract

Mycophenolate mofetil (MM) is an immunosuppressive agent developed and originally used to prevent acute rejection of solid-organ transplantation. There have been preliminary reports of its successful use in the treatment of autoimmune myasthenia gravis (MG). We conducted a double-blind, placebo-controlled pilot trial of MM in the treatment of suboptimally controlled, stable MG. Results of this pilot study are promising and suggestive of greater improvement in the patients who received MM compared to placebo.

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