This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features!

Skip to main page content

Add to Collections

Your saved search

Name of saved search:

Search terms:

Test search terms

Would you like email updates of new search results?

Yes
No

Email: (change)

Frequency:

Which day?

Which day?

Report format:

Send at most:

Send even when there aren't any new results

Optional text in email:

Your RSS Feed

. 2003 Oct 31;302(5646):841.

doi: 10.1126/science.1090278.

alpha-Synuclein locus triplication causes Parkinson's disease

Affiliations

PMID: 14593171
DOI: 10.1126/science.1090278

alpha-Synuclein locus triplication causes Parkinson's disease

A B Singleton et al. Science. 2003.

. 2003 Oct 31;302(5646):841.

doi: 10.1126/science.1090278.

Affiliation

¹ Laboratory of Neurogenetics, National Institute on Aging, Bethesda, MD 20892, USA. singleta@mail.nih.gov

PMID: 14593171
DOI: 10.1126/science.1090278

No abstract available

PubMed Disclaimer

Similar articles

alpha-Synuclein promoter confers susceptibility to Parkinson's disease.
Pals P, Lincoln S, Manning J, Heckman M, Skipper L, Hulihan M, Van den Broeck M, De Pooter T, Cras P, Crook J, Van Broeckhoven C, Farrer MJ. Pals P, et al. Ann Neurol. 2004 Oct;56(4):591-5. doi: 10.1002/ana.20268. Ann Neurol. 2004. PMID: 15455394
Failure to find alpha-synuclein gene dosage changes in 190 patients with familial Parkinson disease.
Gispert S, Trenkwalder C, Mota-Vieira L, Kostic V, Auburger G. Gispert S, et al. Arch Neurol. 2005 Jan;62(1):96-8. doi: 10.1001/archneur.62.1.96. Arch Neurol. 2005. PMID: 15642855
Multiple regions of alpha-synuclein are associated with Parkinson's disease.
Mueller JC, Fuchs J, Hofer A, Zimprich A, Lichtner P, Illig T, Berg D, Wüllner U, Meitinger T, Gasser T. Mueller JC, et al. Ann Neurol. 2005 Apr;57(4):535-41. doi: 10.1002/ana.20438. Ann Neurol. 2005. PMID: 15786467
Gene dosage and pathogenesis of Parkinson's disease.
Eriksen JL, Przedborski S, Petrucelli L. Eriksen JL, et al. Trends Mol Med. 2005 Mar;11(3):91-6. doi: 10.1016/j.molmed.2005.01.001. Trends Mol Med. 2005. PMID: 15760766 Review.
[alpha-Synuclein and familial Parkinson's disease].
Iwatsubo T. Iwatsubo T. No To Shinkei. 1999 Jun;51(6):481-6. No To Shinkei. 1999. PMID: 10423749 Review. Japanese. No abstract available.

See all similar articles

Cited by

The Role of Astrocytes and Alpha-Synuclein in Parkinson's Disease: A Review.
Brash-Arias D, García LI, Pérez-Estudillo CA, Rojas-Durán F, Aranda-Abreu GE, Herrera-Covarrubias D, Chi-Castañeda D. Brash-Arias D, et al. NeuroSci. 2024 Mar 8;5(1):71-86. doi: 10.3390/neurosci5010005. eCollection 2024 Mar. NeuroSci. 2024. PMID: 39483813 Free PMC article. Review.
Inhibition of the Fe(III)-catalyzed dopamine oxidation by ATP and its relevance to oxidative stress in Parkinson's disease.
Jiang D, Shi S, Zhang L, Liu L, Ding B, Zhao B, Yagnik G, Zhou F. Jiang D, et al. ACS Chem Neurosci. 2013 Sep 18;4(9):1305-13. doi: 10.1021/cn400105d. Epub 2013 Jul 17. ACS Chem Neurosci. 2013. PMID: 23823941 Free PMC article.
Fatty Acid-Binding Protein 3 Expression in the Brain and Skin in Human Synucleinopathies.
Oizumi H, Yamasaki K, Suzuki H, Hasegawa T, Sugimura Y, Baba T, Fukunaga K, Takeda A. Oizumi H, et al. Front Aging Neurosci. 2021 Mar 25;13:648982. doi: 10.3389/fnagi.2021.648982. eCollection 2021. Front Aging Neurosci. 2021. PMID: 33841128 Free PMC article.
Mutant A53T α-Synuclein Improves Rotarod Performance Before Motor Deficits and Affects Metabolic Pathways.
Guerreiro PS, Coelho JE, Sousa-Lima I, Macedo P, Lopes LV, Outeiro TF, Pais TF. Guerreiro PS, et al. Neuromolecular Med. 2017 Mar;19(1):113-121. doi: 10.1007/s12017-016-8435-5. Epub 2016 Aug 17. Neuromolecular Med. 2017. PMID: 27535567
Genetic perspective on the role of the autophagy-lysosome pathway in Parkinson disease.
Gan-Or Z, Dion PA, Rouleau GA. Gan-Or Z, et al. Autophagy. 2015;11(9):1443-57. doi: 10.1080/15548627.2015.1067364. Autophagy. 2015. PMID: 26207393 Free PMC article. Review.

See all "Cited by" articles

Publication types

Actions

MeSH terms

Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions

Substances

Actions
Actions
Actions
Actions

LinkOut - more resources

Full Text Sources
- Atypon
- Ovid Technologies, Inc.
Other Literature Sources
- H1 Connect - Access expert opinions and insights on biomedical research.
- The Lens - Patent Citations Database
Medical
- MedlinePlus Health Information
Research Materials
- Coriell Cell Repositories
Miscellaneous
- NCI CPTAC Assay Portal