Drug induced QT prolongation and torsades de pointes
- PMID: 14594906
- PMCID: PMC1767957
- DOI: 10.1136/heart.89.11.1363
Drug induced QT prolongation and torsades de pointes
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References
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- De Ponti F, Poluzzi E, Montanaro N, et al. QTc and psychotropic drugs. Lancet 2000;356:75–6. - PubMed
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- Wysowski DK, Bacsanyi J. Cisapride and fatal arrhythmia. N Engl J Med 1996;335:290–1. - PubMed
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- Dapro B. Spectrum of drugs prolonging QT interval and the incidence of torsades de pointes. Eur Heart J 2001;3(suppl K):K70–80. ▸ A good review providing an insight into the incidence of drug induced TdP.
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- Antzelevitch C, Sicouri S. Clinical relevance of cardiac arrhythmias generated by afterdepolarisation: role of M cells in the generation of U wave, triggered activity, and torsades de pointes. J Am Coll Cardiol 1994;23:259–77. ▸ An important study that demonstrated the cellular mechanism of drug induced QT prolongation and TdP. - PubMed
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- Roden DM. Torsades de pointes. Clin Cardiol 1993;16:683–6. - PubMed
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