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. 1978 Jan 15;34(1):84-5.
doi: 10.1007/BF01921917.

Effects of streptozotocin on early rat embryos grown in culture

E M Deuchar

Effects of streptozotocin on early rat embryos grown in culture

E M Deuchar. Experientia. .

Abstract

Addition of 1 mg/ml streptozotocin to serum in which 10-day rat embryos are cultured reduces their growth and viability. There is therefore a risk that administration of this drug to pregnant animals to induce diabetes could also have direct, deleterious effects on the embryos.

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