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. 2003 Nov 13;5(23):4373-6.
doi: 10.1021/ol035655u.

Palladium-catalyzed intermolecular coupling of aryl chlorides and sulfonamides under microwave irradiation

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Palladium-catalyzed intermolecular coupling of aryl chlorides and sulfonamides under microwave irradiation

George Burton et al. Org Lett. .

Abstract

[reaction: see text] An efficient intermolecular N-arylation of sulfonamides with aryl chlorides is realized using palladium catalysis. The reaction proceeds under microwave irradiation at 180-200 degrees C for 10 min with 2-10 mol % of Pd catalyst in 32-85% isolated yields.

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