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. 2003 Nov;41(11):5195-8.
doi: 10.1128/JCM.41.11.5195-5198.2003.

Genetic characterization of newly reintroduced dengue virus type 3 in Martinique (French West Indies)

Christophe N Peyrefitte  1 , Patricia Couissinier-Paris, Véronique Mercier-Perennec, Maël Bessaud, Jenny Martial, Nadia Kenane, Jean-Paul A Durand, Hugues J Tolou
Affiliations

Genetic characterization of newly reintroduced dengue virus type 3 in Martinique (French West Indies)

Christophe N Peyrefitte et al. J Clin Microbiol. 2003 Nov.

Abstract

Dengue type 3 viruses were isolated from patients in Martinique between 1999 and 2002. This serotype had not been detected on the island in the last 20 years. Genomic sequence determination and analysis showed great stability of the virus during the period studied.

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Figures

FIG. 1.
FIG. 1.
Phylogenetic tree of DENV-3 based on complete nucleotide sequences. Phylograms were constructed with the MEGA program (8) by using the Jukes-Cantor algorithm and the neighbor-joining method. The percentage of successful bootstrap replicates (500 bootstrap replications, confidence probability greater than 90%) is indicated at nodes. The length of branches is proportional to the number of nucleotide changes (percent divergence). The strains sequenced in this work are indicated by asterisks.
FIG. 2.
FIG. 2.
Phylogenetic tree of DENV-3 strains based on prM/M and partial E nucleotide sequences (nucleotides 437 to 1144). For the Mexican isolate, only the sequence between positions 437 and 766 was available. The strains sequenced in this work are indicated by asterisks. Dark triangles correspond to viruses of the same subtype clustering together. DENV-1 and -2 sequences were introduced for correct rooting of the tree.
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