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. 2003 Nov-Dec;11(6):683-6.
doi: 10.1176/appi.ajgp.11.6.683.

Frontal behavioral syndromes and functional status in probable Alzheimer disease

Julie C Stout  1 , Mary F Wyman, Shannon A Johnson, Guerry M Peavy, David P Salmon
Affiliations

Frontal behavioral syndromes and functional status in probable Alzheimer disease

Julie C Stout et al. Am J Geriatr Psychiatry. 2003 Nov-Dec.

Abstract

Objective: /

Method: The authors used the Frontal Systems Behavior Scale (FrSBe) to determine the frequency of frontal behavioral syndromes in 49 subjects with mild-to-moderate dementia and 23 subjects with severe dementia of Alzheimer disease (AD) and 23 healthy control (HC) participants.

Results: /

Conclusions: Frontal behavior syndromes occurred with higher frequency in AD. Apathy and executive dysfunction were elevated both in mild-to-moderate and severe AD. Disinhibition was elevated only in severe AD. In AD, apathy was associated with difficulty in basic activities of daily living (ADL), whereas executive dysfunction was related to impairment in instrumental ADLs.

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