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Clinical Trial
. 2003 Nov;88(11):974-5.
doi: 10.1136/adc.88.11.974.

Vitamin K supplementation in cystic fibrosis

Affiliations
Clinical Trial

Vitamin K supplementation in cystic fibrosis

J H L van Hoorn et al. Arch Dis Child. 2003 Nov.

Abstract

The relation between different doses of vitamin K supplementation, several bone markers, and PIVKA-II concentrations in cystic fibrosis (CF) patients compared to controls was evaluated. Results suggest that a increased vitamin K intake may have significant health benefits for children with CF.

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Figures

Figure 1
Figure 1
Boxplot showing total osteocalcin (t-OC in black), undercarboxylated osteocalcin (u-OC in grey), and carboxylated osteocalcin (c-OC in white) for vitamin K supplementation in CF patients, compared to healthy controls. Vitamin K supplementation is shown in three different groups: CFno = no supplementation; CFlow = <0.25 mg/day; and CFhigh = ⩾1 mg/day. Significant p values are shown.
Figure 2
Figure 2
Boxplot showing PIVKA-II concentrations in CF patients with three different doses of vitamin K supplementation, compared to healthy controls. Significant p values are shown.

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