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. 2003 Oct 21;1(1):22.
doi: 10.1186/1477-7819-1-22.

Pulmonary malignant granular cell tumor

Ming Jiang  1 , Timothy Anderson, Chukwumere Nwogu, Dongfeng Tan
Affiliations

Pulmonary malignant granular cell tumor

Ming Jiang et al. World J Surg Oncol. .

Abstract

BACKGROUND: Malignant granular cell tumor (MGCT) is a rare disease entity. Forty-one well-documented MGCTs have been reported in the world literature. CASE REPORT: This report describes a patient who presented with a MGCT of the lung and reviews the preoperative evaluation, pathologic features and differential diagnosis of the disease. This case represents the first report of resected primary pulmonary MGCT. CONCLUSIONS: Diagnosis of MGCT is based on histology of the primary tumor, immunohistochemistry, and exclusion of tumors that may mimic granular cell tumor.

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Figures

Figure 1
Figure 1
Chest radiograph showing a mass lesion (arrow) intimately associated with a segmental bronchus of the left lower lobe.
Figure 2
Figure 2
Chest computed tomogram showing localized expansion of mass, which measured 2.8 × 2.0 cm in size.
Figure 3
Figure 3
Microscopically, the tumor was made of sheets of granular cells with moderate atypia, prominent spindling, increased nuclear/cytoplasm ratio and greater pleomorphism. Note two giant tumor cells were in the central field of the photograph. (Hematoxylin and eosin; × 400)
See this image and copyright information in PMC

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