Priming the hematopoietic pump
- PMID: 14614848
- DOI: 10.1016/s1074-7613(03)00302-9
Priming the hematopoietic pump
Abstract
Markers of multiple hematopoietic lineages are expressed in multipotent progenitors, a phenomenon referred to as "lineage priming." A new study in this issue of Immunity provides compelling evidence that such "promiscuous" gene expression occurs in hematopoietic stem cells and does not interfere with their long-term repopulation potential.
Comment on
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Hematopoietic stem cells expressing the myeloid lysozyme gene retain long-term, multilineage repopulation potential.Immunity. 2003 Nov;19(5):689-99. doi: 10.1016/s1074-7613(03)00299-1. Immunity. 2003. PMID: 14614856
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