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Comment
. 2003 Nov;19(5):633-4.
doi: 10.1016/s1074-7613(03)00302-9.

Priming the hematopoietic pump

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Free article
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Priming the hematopoietic pump

Stuart H Orkin. Immunity. 2003 Nov.
Free article

Abstract

Markers of multiple hematopoietic lineages are expressed in multipotent progenitors, a phenomenon referred to as "lineage priming." A new study in this issue of Immunity provides compelling evidence that such "promiscuous" gene expression occurs in hematopoietic stem cells and does not interfere with their long-term repopulation potential.

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